I think it really depends on your content and how you get and curate your list(s). They just really want to make sure people are opt-in, I think. I don’t have a ton of affiliate experience with them, but I know if you ask them direct questions they’re happy to give you a straight answer.
As for Madmimi, I like the simplicity. It doesn’t have a ton of complicated stuff for setting up or making the design, yet it has a lot of add-ons you can switch on and off on a whim. Madmimi has also shown a great deal of support in my limited experience with them, so they’re a really easy recommend for users who don’t want a lot of extras.